Funded by the European Union (GA 101072980) and supported by the UK Engineering and Physical Sciences Research Council. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.

Gökçe Özkul

Gökçe Özkul

DC 3 - CRISPR-based RNA editing tools for cell-free biosensors.

About your project

My DC project aims to increase the sensitivity and specificity in the detection of analyte molecules using optimized cell-free systems functioning through CRISPR-Cas actuator Cas7-11.

About you

Since my early education years, science, technology, and innovation have been my strong interests. I have completed by Bachelor’s degree in Middle East Technical University (METU, Turkey) in the Department of Environmental Engineering, in 2018. During my time as an undergraduate student, I contributed as a project assistant in the study of a faculty member, which provided me an insight into the academia and research. Hence, I have always valued contributing to developing new technologies and techniques for the future world. 

Therefore, after I graduated as an environmental engineer, I started my Master’s education in Synthetic Biology in Turkey’s leading laboratory, Synthetic Biosystems Laboratory (SBL/Şeker Lab in Bilkent University) with the ambition of being able to explore and develop. By the time I completed my Master’s studies in 2021, I was practically capable of molecular cloning techniques and designs, recombinant protein overexpression, purification and characterization, advanced analysis tools such as SEM, TEM, LCMS-QTOF, and data analysis for experiment results. As Richard Feynman once said, “What I cannot create, I do not understand”, cell-free systems are great ways to understand cell structure and functionality from a bottom-up viewpoint. The modularity and flexibility of cell-free systems allow greater control and suitability to various application areas. As a graduate student who combined engineering and synthetic biology, one of my motivations is to be involved in a multi-disciplinary work environment where I believe I can contribute both with my engineering and synthetic biology background. In this regard, I look forward to gaining experience and developing biosensors through cell-free synthetic biology for future application areas with the supervision of SYNSENSO.

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